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Gli1 cells

Scientists find culprit responsible for calcified blood vessels in kidney disease

Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease. The research will guide future studies into ways to block minerals from building up inside blood vessels and exacerbating atherosclerosis, the h...
Reproductive Health

New center focuses on women’s and men’s reproductive health

A new center at Washington University School of Medicine in St. Louis aims to bring together a cadre of faculty members to conduct basic, translational and clinical research focused on reproductive health. The center, one of only a handful of medical-school based facilities focused on...
Axons Myelin

Beneficial role clarified for brain protein associated with mad cow disease

Scientists have clarified details in understanding the beneficial function of a type of protein normally associated with prion diseases of the brain, such as bovine spongiform encephalopathy (commonly known as mad cow disease) and its human counterpart, variant Creutzfeldt-Jakob disea...
Rithwick Rahjagopal, MD, PhD and Clay F. Semenkovich, MD

Rajagopal awarded Young Physician-Scientist honor

Rithwick Rajagopal, MD, PhD, an assistant professor of ophthalmology and visual sciences at Washington University School of Medicine in St. Louis, has received a Young Physician-Scientist Award from the American Society for Clinical Investigation. Rajagopal, working with Clay F. Semen...
Aorta

Genetic error that increases risk of aortic rupture identified

A study led by Washington University School of Medicine in St. Louis, in collaboration with Brigham and Women’s Hospital in Boston, has identified a genetic error that weakens the aorta, placing patients with this and similar errors at high risk of aortic aneurysms and ruptures. The f...
Genetic Master Switch

New clues found to immune system’s misfiring in autoimmune diseases

A person’s genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. But little is known about how immune cells are pushed into overdrive. Now, in new research that points to potential therapeutic tar...
Clay F. Semenkovich, MD

Clay F. Semenkovich, M.D. Receives the American Diabetes Association’s 2016 Edwin Bierman Award

Congratulations to Clay F. Semenkovich, M.D. who was named the 2016 recipient of the Edwin Bierman Award by the American Diabetes Association. This lecture is awarded in honor of the memory of Edwin L. Bierman, MD. Dr. Bierman was an exemplary scientist, mentor and leader in the field...
Jeffery R. Millman, PhD

Stem cells from diabetic patients coaxed to become insulin-secreting cells

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes. People with this form of diabetes can’...
Rithwick Rahjagopal, MD, PhD and Clay F. Semenkovich, MD

Nerve injury appears to be root of diabetes-related vision loss

Diabetes-related vision loss most often is blamed on blood vessel damage in and around the retina, but new research indicates that much of that vision loss may result from nerve cell injury that occurs long before any blood vessels are damaged. The finding — from scientists at Washing...
Jean E. Schaffer, MD

Jean E. Schaffer, MD recipient of Distinguished Investigator Award

Jean E. Schaffer, MD, the Virginia Minnich Distinguished Professor of Medicine and Director of the Diabetes Research Center and Diabetic Cardiovascular Disease Center, is recognized for her distinguished contributions advancing the understanding of cardiovascular pathophysiology in me...