Diabetes Research Center (DRC)
Washington University in St. Louis


Main page of DRC site, legends in text below.

Legends (clockwise from top left)

  1. DRC Past Director & Associate Director M. Alan Permutt, M.D. with Washington University School of Medicine Diabetes Day 2011 guest speaker Michael W. Schwartz, M.D., University of Washington.
  2. A single adult human islet demonstrating proliferating b- and non-b-cells. Paraffin section of intact islet. Ki-67 (red), DAPI (blue) and insulin (green) (image courtesy of the McDaniel Laboratory).
  3. Washington University in St. Louis School of Medicine Diabetes Day 2011 Poster Presentation.
  4. Lipid droplets stained with Nile Red from the fat tissue of a fruit fly larvae that has been eating a high sugar diet. The dark areas are the nuclei of individual cells (image courtesy of the Baranski Laboratory).
  5. Foam cells (image courtesy of the Bernal Laboratory).
  6. Vascular cross section (Image courtesy of the Bernal Laboratory).
  7. Adult human islets dispersed into single cells demonstrating proliferating and non-proliferating b-cells. Ki-67 (red), DAPI (blue) and insulin (green) (Image courtesy of the McDaniel Laboratory).


Please acknowledge the Washington University DRC in your publications as follows: "Supported by DRC, Grant No. P30 DK020579"


Current DRC Pilot and Feasibility Projects




Present Position


Charles Harris, MD, PhD

GR post-translational modification in adipogenesis and adipocyte function

Assistant Professor, Endocrinology, Metabolism & Lipid Research


Jason Held, PhD

Thiolproteomic characterization of in vivo cysteine redox sensors in diabetes

Assistant Professor, Oncology


Joel Schilling, MD, PhD

Macrophage PPAR gamma as a regulator of ischemic cardiac remodeling

Assistant Professor, Cardiology


Boris Calderon, MD

Tracing the ontogeny and turnover rate of islet resident macrophages

Assistant Professor, Pathology & Immunology


Brian Finck, PhD

Mitochondrial pyruvate transport and beta cell function

Assistant Professor, Nutritional Sciences


Simon Haroutounian, PhD

Predicting individual response to analgesic treatment in painful diabetic neuropathy and improving nonverbalassessment of pain relief

Assistant Professor, Anesthesiology


Colin Nichols, PhD

Zebrafish model of excitability-driven diabetes

Professor, Cell Biology & Physiology


M. Yanina Pepino de Gruev, PhD

Metabolic effects of non-nutritive sweeteners

Assistant Professor, Nutritional Sciences