Department of Medicine and Cell Biology
Mailing Address Center for Human Nutrition
Campus Box 8031
660 S. Euclid Ave.
St. Louis, MO 63110
Office Location 212 West Building
Office Phone (314) 747-0348
Lab Phone (314) 362-8206
Fax (314) 362-8109
Metabolic Regulation and Obesity
Signal Transduction/Hormone Action
Islet Biology and Immunology
Category(ies) of Research:
Descriptor of Research:
Research in my group is focused on the role of fatty acid uptake and utilization in the cellular response to stress and how this influences development of abnormalities linked to Diabetes and the metabolic syndrome. In particular we are interested in how these processes are impacted by alterations in the cellular trafficking and turnover of the membrane protein CD36, which has been implicated in complications of insulin resistance. On the translational level we are interested in studying the functional impact of polymorphisms in the CD36 gene and how they can impact individual variability of lipid utilization and susceptibility to metabolic disease.